It's the early days of the Global Outbreak, and the few states with active ZERO (Zombie Emergency Reaction Organization) teams have been folded into the reorganized Hangar-18, the Federal Department in charge of Supernatural Phenomena.
During the Bush administration, H-18 was corrupted by the PNSC-Project for the New Satanic Century- a group of hard-line America firsters willing to sell our national soul to the devil for power. The new administration appointed a reformer--the mysterious Simon Abraxas-- to head up the department and ferret out what infernalists still remain.
That's all abstract and far away, though. The players are members of the newly formed ZERO-HI team, tasked to contain zombie outbreaks throughout the State of Hawaii. In spite of the state's tiny size, it's a very critical task -- the state's international nature and ties to Asia make it a key entry point for infected, and any outbreak could easily overrun one or more of the islands in a matter of days.
If you're in the ZERO Team, expect things to be brutal. The dead hate the living, and ZERO...hates the dead.